Maxcy Gregg was born in Columbia, South Carolina August 1st 1814. He attended South Carolina College, and after passing the bar practiced law with his father. When the Mexican – American War started Gregg served as a Major in the 12th United States Infantry. In the years leading up to the Civil War he was an advocate of secessionists. He wrote a pamphlet called, "An Appeal to the State Rights Party of South Carolina."
In December 1860, when South Carolina seceded, Gregg went to work organizing the 1st South Carolina, a six month regiment. He served as their Colonel. The 1st took part in the bombing of Fort Sumter. He would move up to become Brigadier General on December 14th 1862; he took command of a brigade made up of South Carolina regiments in Confederate General Ambrose Powell Hill’s Division at the Battles of Gaines’ Mills and Second Manassas. While fighting at the Battle of Antietam, Gregg was wounded in the thigh by the same bullet which had killed Confederate Brigadier General Lawrence O’Bryan Branch.
While fighting at the Battle of Fredericksburg, Gregg was commanding at a point in the Confederate line where there was a gap. Union Major General George Gordon Meade’s soldiers were attacking that part of line lines. As Gregg rallied his troops a bullet passed through his body, hitting his spine. He died two days later on December 15th 1862. Gregg is buried in the Elmwood Cemetery in Columbia, South Carolina.